Nafisa M. Jadavji, Ph.D. - Principal Investigator
Assistant Professor, Department of Biomedical Sciences, Midwestern University
Adjunct Research Professor, Department of Neuroscience, Carleton University
Assistant Research Professor, Department of Child Health, College of Medicine – Phoenix, University of Arizona
Curriculum Vitae
Dr. Nafisa M. Jadavji is a Neuroscientist. She is an Assistant Professor at Midwestern University, Research Professor at the University of Arizona, and Carleton University. In 2012, she completed her doctoral training at McGill University in Montréal, Canada. Currently, her laboratory investigates how the brain responds to different biological processes throughout the lifespan. More specifically, her lab studies how the brain responds to changes in one-carbon metabolism, with a specific focus on maternal nutrition contributions to offspring neurodevelopment, neurological diseases (e.g. ischemic stroke and vascular dementia), and aging.
Dr. Jadavji has received funding from the Arizona Department of Health, American Heart Association (US), Federation of European Neuroscience Society (Europe), NeuroWIND (Germany), Canadian Association for Neuroscience, Canadian Institutes of Health Research, National Science & Engineering Research Council (Canada), International Brain Research Organization, Parkinson's disease Foundation (US), Burroughs Wellcome Fund (US) and Fonds de la recherché en santé Québec (Canada).
Dr. Jadavji’s research has been published in Biochemical Journal, Neuroendocrinology, Experimental Neurology, Journal of Neuroscience, Human Molecular Genetics, Nutrition Reviews, Toxicological Science, European Journal of Neuroscience, Neural Regeneration Research, Nutritional Neuroscience, Nutrients, and Neurobiology of Disease. She has also posted several preprints as an early career researcher. Dr. Jadavji has published 53 peer review papers.
Dr. Jadavji has supervised and mentored over 50 undergraduate, graduate, and postdocs so far during her scientific career.
Dr. Jadavji is an Editorial member for Scientific Reports (Editor), Frontiers in Nutrition and Neuroscience (Associate Editor), Bioprotocols (Associate Editor), Metabolites (Review Editor) journals. She is the Finance and Vice Chair of the Board of Directors for the Journal of Young Investigators (JYI) and Chair of the Advisory Board for Reproducibility for Everyone (R4E). Dr. Jadavji is also the Vice President of the Graduate Women in Science and the Events Chair for the Association for Nutrition Early Career Research Group.
When she is not in the laboratory, teaching, or writing, Dr. Jadavji enjoys to cooking and baking gluten free treats. She is also an avid traveler, runner, and knitter.
Assistant Professor, Department of Biomedical Sciences, Midwestern University
Adjunct Research Professor, Department of Neuroscience, Carleton University
Assistant Research Professor, Department of Child Health, College of Medicine – Phoenix, University of Arizona
Curriculum Vitae
Dr. Nafisa M. Jadavji is a Neuroscientist. She is an Assistant Professor at Midwestern University, Research Professor at the University of Arizona, and Carleton University. In 2012, she completed her doctoral training at McGill University in Montréal, Canada. Currently, her laboratory investigates how the brain responds to different biological processes throughout the lifespan. More specifically, her lab studies how the brain responds to changes in one-carbon metabolism, with a specific focus on maternal nutrition contributions to offspring neurodevelopment, neurological diseases (e.g. ischemic stroke and vascular dementia), and aging.
Dr. Jadavji has received funding from the Arizona Department of Health, American Heart Association (US), Federation of European Neuroscience Society (Europe), NeuroWIND (Germany), Canadian Association for Neuroscience, Canadian Institutes of Health Research, National Science & Engineering Research Council (Canada), International Brain Research Organization, Parkinson's disease Foundation (US), Burroughs Wellcome Fund (US) and Fonds de la recherché en santé Québec (Canada).
Dr. Jadavji’s research has been published in Biochemical Journal, Neuroendocrinology, Experimental Neurology, Journal of Neuroscience, Human Molecular Genetics, Nutrition Reviews, Toxicological Science, European Journal of Neuroscience, Neural Regeneration Research, Nutritional Neuroscience, Nutrients, and Neurobiology of Disease. She has also posted several preprints as an early career researcher. Dr. Jadavji has published 53 peer review papers.
Dr. Jadavji has supervised and mentored over 50 undergraduate, graduate, and postdocs so far during her scientific career.
Dr. Jadavji is an Editorial member for Scientific Reports (Editor), Frontiers in Nutrition and Neuroscience (Associate Editor), Bioprotocols (Associate Editor), Metabolites (Review Editor) journals. She is the Finance and Vice Chair of the Board of Directors for the Journal of Young Investigators (JYI) and Chair of the Advisory Board for Reproducibility for Everyone (R4E). Dr. Jadavji is also the Vice President of the Graduate Women in Science and the Events Chair for the Association for Nutrition Early Career Research Group.
When she is not in the laboratory, teaching, or writing, Dr. Jadavji enjoys to cooking and baking gluten free treats. She is also an avid traveler, runner, and knitter.
Alisha Harrison, BA – Sr. Research Specialist
Alisha is a Senior Research Specialist in Dr. Jadavji’s lab. Originally from Kentucky, she earned her bachelor’s degree in biology from Berea College. While seeking her degree, Alisha completed research internships in molecular biology at the University of Louisville and Vanderbilt University. After graduation, Alisha worked as a laboratory technician in Biochemistry at the University of Kentucky before joining Midwestern University in 2012. Alisha has developed key skills in molecular biology such as DNA sequencing, cell culture, and bacterial and fungal microbiology. Alisha joined Dr. Jadavji’s lab in 2023 hoping to develop new skills while using her previous lab experience to advance the lab’s research goals.
Alisha is a Senior Research Specialist in Dr. Jadavji’s lab. Originally from Kentucky, she earned her bachelor’s degree in biology from Berea College. While seeking her degree, Alisha completed research internships in molecular biology at the University of Louisville and Vanderbilt University. After graduation, Alisha worked as a laboratory technician in Biochemistry at the University of Kentucky before joining Midwestern University in 2012. Alisha has developed key skills in molecular biology such as DNA sequencing, cell culture, and bacterial and fungal microbiology. Alisha joined Dr. Jadavji’s lab in 2023 hoping to develop new skills while using her previous lab experience to advance the lab’s research goals.
Sharadyn Ille, B.S. – Doctor of Dental Medicine Student
Sharadyn is a Dental Student at Midwestern University, originally from Cincinnati, Ohio. She received a bachelor’s degree in Health Sciences and a minor in Biology at The Ohio State University. During her time there, she worked as a research assistant at the Leukemia Tissue Bank, cryopreserving samples of leukocytes from cancer patients. She is excited to become a member of the Jadavji lab and take on a new area of research! During her free time, she enjoys hiking, playing volleyball, and spending time with friends.
Publications:
1. Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023). Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. Nutrients. 15:1556 (Invited)
2. PREPRINT Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. https://www.biorxiv.org/content/10.1101/2023.02.15.528759v1
Sharadyn is a Dental Student at Midwestern University, originally from Cincinnati, Ohio. She received a bachelor’s degree in Health Sciences and a minor in Biology at The Ohio State University. During her time there, she worked as a research assistant at the Leukemia Tissue Bank, cryopreserving samples of leukocytes from cancer patients. She is excited to become a member of the Jadavji lab and take on a new area of research! During her free time, she enjoys hiking, playing volleyball, and spending time with friends.
Publications:
1. Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023). Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. Nutrients. 15:1556 (Invited)
2. PREPRINT Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. https://www.biorxiv.org/content/10.1101/2023.02.15.528759v1
Sanika Joshi, MBS – Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)
Sanika is a medical student at Midwestern University interested in the field of neurology, public health, and nutrition. She was raised in California and attended the University of California, Irvine where she graduated with honors in Public Health Science. While pursuing her undergraduate education, Sanika worked on numerous research projects such as studying the behavior of microbial communities in a Cystic Fibrosis lung model, understanding variation in pain sensitivity in different cultures, and even conducting an epidemiological study to determine how climate change affects various populations across California. She has a passion for learning and enjoys running long-distance, baking, reading books, and going on long hikes in her free time. She is excited to understand how nutrition plays a key role in affecting brain health as a part of the Jadavji lab! |
Faizan Anwar, BS – Doctor of Osteopathic Medicine Student
I am First Year Osteopathic Medicine student. I earned his bachelor’s degree in neuroscience. I was previously involved in research that investigated cortical morphometric changes in patients with schizophrenia. With my interest in neuroscience and psychiatry, I was also researching molecular changes in the amygdala, hippocampus and cortex that are involved in post-traumatic stress disorder in murine models of acute respiratory distress syndrome. In my free time, I enjoy the company of my friends and family
I am First Year Osteopathic Medicine student. I earned his bachelor’s degree in neuroscience. I was previously involved in research that investigated cortical morphometric changes in patients with schizophrenia. With my interest in neuroscience and psychiatry, I was also researching molecular changes in the amygdala, hippocampus and cortex that are involved in post-traumatic stress disorder in murine models of acute respiratory distress syndrome. In my free time, I enjoy the company of my friends and family
Mary-Tyler Mosley - Undergraduate Student
Mary-Tyler is an undergraduate student at Stanford University where she studies Human Biology with an emphasis on Brain and Behavior. Previously, she has participated in research centered on genetic mutations in neurodegenerative diseases including Parkinson's Disease and Alzheimer's Disease. And now, Mary-Tyler is very excited to work with the Jadavji Lab and explore a new area of neurobiology! Though when not actively tackling academic pursuits, she also enjoys participating in performance arts such as theatre, dance, and music.
Mary-Tyler is an undergraduate student at Stanford University where she studies Human Biology with an emphasis on Brain and Behavior. Previously, she has participated in research centered on genetic mutations in neurodegenerative diseases including Parkinson's Disease and Alzheimer's Disease. And now, Mary-Tyler is very excited to work with the Jadavji Lab and explore a new area of neurobiology! Though when not actively tackling academic pursuits, she also enjoys participating in performance arts such as theatre, dance, and music.
Siddarth (Sidd) Gunnala, BS - Master's of Biomedical Science Student
Siddarth is a student in the Masters of Biomedical Sciences at Midwestern University. Born and raised in Phoenix, Arizona, he attended the University of Arizona where he obtained a degree in Molecular and Cellular Biology. During his undergraduate career, Siddarth involved himself in research that explored Model-Based Reasoning and its application in a collegiate education setting. He enjoys weight-lifting, football, gardening, and traveling during his spare time. He is excited to join the Jadavji lab and develop a deeper understanding in the field of neurology! 
Manogna Nuthi, BS - Doctor of Osteopathic Medicine Student
Manogna Nuthi is a medical student at Midwestern University. She is interested in neuroscience, nutrition, and surgery. For her undergraduate degree, she attended the University of Texas at Dallas, where she graduated with a Bachelor of Science degree in Neuroscience. She also completed her Master of Science degree in Medical Sciences at the University of North Texas Health Science Center. During her undergraduate experience, she was involved in a neuroplasticity lab exploring the applications of Vagal Nerve Therapy in improving auditory disorders and speech deficits such as hearing loss, autism related speech deficits, and VPA altered speech deficits. She primarily handled animal surgeries and animal health with additional tasks in brain mapping, behavioral experimentation, and micro-construction of devices for related projects. She is very excited to expand her neurobiology understanding through Dr. Jadavji’s lab. Outside of academic work, Manogna is an avid Indian classical dancer and enjoys baking, movies, badminton, and spending time with family and friends. |
Amanda Covaleski, B.S. – Doctor of Pharmacy Student - Research Assistant
Amanda is a Pharmacy Student at Midwestern University. She is from Lancaster, Pennsylvania and went to the Pennsylvania State University to receive a Bachelor of Science degree in Biology. Previously, Amanda has done research in Costa Rica on local flora and fauna. She enjoys her free time by painting, cooking, traveling, gardening, and spending quality time with friends and family. In addition, she is very excited to grow and learn more about neurobiology through the Jadavji Lab!
Amanda is a Pharmacy Student at Midwestern University. She is from Lancaster, Pennsylvania and went to the Pennsylvania State University to receive a Bachelor of Science degree in Biology. Previously, Amanda has done research in Costa Rica on local flora and fauna. She enjoys her free time by painting, cooking, traveling, gardening, and spending quality time with friends and family. In addition, she is very excited to grow and learn more about neurobiology through the Jadavji Lab!
Petter Burrows, B.S. - College of Veterinary Medicine Fellow 2023
My name is Petter and I am currently studying veterinary medicine here at Midwestern University. I'm originally from Seattle, Washington, and went to Occidental College in Los Angeles, where I obtained a degree in biochemistry. I have a passion for animals, in particular my shy, but very sweet lab mix, who is living with me here in Arizona. I enjoy skiing, golfing and hiking or anything that involves a group of friends. I look forward to expanding my understanding of 1C metabolism within ischemic stroke brain tissue as a member of the Jadavji lab.
My name is Petter and I am currently studying veterinary medicine here at Midwestern University. I'm originally from Seattle, Washington, and went to Occidental College in Los Angeles, where I obtained a degree in biochemistry. I have a passion for animals, in particular my shy, but very sweet lab mix, who is living with me here in Arizona. I enjoy skiing, golfing and hiking or anything that involves a group of friends. I look forward to expanding my understanding of 1C metabolism within ischemic stroke brain tissue as a member of the Jadavji lab.
Abbey McKee, MBS - Doctor of Osteopathic Medicine Student
Abbey is a medical student at Midwestern University in Glendale, AZ with interests in surgical specialties. She received her B.S. in biology with a chemistry minor from Heidelberg University in Tiffin, OH. While in pursuit of her degree, Abbey was a 4-year varsity softball letterman and completed an internship with OrthoNeuro in New Albany, OH. After graduation, Abbey attended Midwestern University in Downers Grove, IL to receive her Master of Biomedical Sciences where her thesis focused on characterizing unique expression profiles of cell sorted mammalian cells that were transfected with non-viral plasmid DNA. She then returned home to Cincinnati, OH to work at Cincinnati Children’s Hospital’s Research Flow Cytometry Core Facility until beginning her medical school curriculum. Abbey is enthusiastic about joining Dr. Jadavji’s lab and expanding her knowledge of neurobiology. During her downtime, Abbey enjoys being outdoors, watching movies, and spending time with friends and family.
Abbey is a medical student at Midwestern University in Glendale, AZ with interests in surgical specialties. She received her B.S. in biology with a chemistry minor from Heidelberg University in Tiffin, OH. While in pursuit of her degree, Abbey was a 4-year varsity softball letterman and completed an internship with OrthoNeuro in New Albany, OH. After graduation, Abbey attended Midwestern University in Downers Grove, IL to receive her Master of Biomedical Sciences where her thesis focused on characterizing unique expression profiles of cell sorted mammalian cells that were transfected with non-viral plasmid DNA. She then returned home to Cincinnati, OH to work at Cincinnati Children’s Hospital’s Research Flow Cytometry Core Facility until beginning her medical school curriculum. Abbey is enthusiastic about joining Dr. Jadavji’s lab and expanding her knowledge of neurobiology. During her downtime, Abbey enjoys being outdoors, watching movies, and spending time with friends and family.
Brooklynn Flynn, BSc - Doctor of Osteopathic Medicine Student
Brooklynn is a first-year Osteopathic Medicine student at Midwestern University. She is from Los Angeles, California. Brooklynn attended University of California, Irvine, where she received a Bachelor of Science in Mathematics with a Specialization in Mathematical Biology. As an undergraduate, Brooklynn worked as a research assistant in the Molloi Imaging Physics lab, working on validating low-dose radiation techniques. In her free time, Brooklynn enjoys playing her guitar, gardening, hiking, and spending time with her cat, Pascal. She is interested in endocrinology, addiction medicine, and surgery. Brooklynn appreciates the opportunity to work in the Jadavji Lab and to grow professionally in a new research field. |
Jadavji Lab Alumni
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1. Yahn GB, Leoncio J, Jadavji NM The role of dietary supplementation of one-carbon metabolism on stroke
outcome. Current Opinion in Clinical Nutrition and Metabolic Care: doi: 10.1097/MCO.0000000000000743 (invited)
Publications
Publication
1. Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM. (2020) The antioxidant role of one- carbon
metabolism on stroke. Antioxidants. 9(11):1141 (invited)
Publication
1. Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM. (2020) The antioxidant role of one-carbon
metabolism on stroke. Antioxidants. 9(11):1141 (invited)
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1. Al Rubaye H, Adamson C, Jadavji NM (2020) The role of maternal diet on offspring gut microbiota
development. Journal of Neuroscience Research. PMID: 32112450
Publications:
- Lilah Manfredi, High School Student Volunteer
- Alice Yaldiko, BS – Doctor of Osteopathic Medicine Student
- Himmat Dhillon, B.Sc. – Doctor of Osteopathic Medicine Student
- Kasey Pull, B.A. - Lab Specialist
- Hurley L, Pull K, Jadavji NM (2022) Immunotherapies for Ischemic Stroke. Immunotherapy: Cancer and Beyond. Editors: Deshmukh and Lamichhane. (invited).
- Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM. Maternal dietary choline deficiencies during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. https://www.biorxiv.org/content/10.1101/2022.08.23.505040v1
- Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448
- PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring. https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1
- Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. Nutrients. 15:1556 (Invited)
- PREPRINT Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. https://www.biorxiv.org/content/10.1101/2023.02.15.528759v1
- Lauren Hurley, B.Sc.- Research Assistant (College of Veterinary Medicine Fellow Summer 2022)
Publications:
- Hurley L, Pull K, Jadavji NM (2022) Immunotherapies for Ischemic Stroke. Immunotherapy: Cancer and Beyond. Editors: Deshmukh and Lamichhane. (invited).
- Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.
- PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring. https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1
- Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. Nutrients. 15:1556 (Invited)
- PREPRINT: Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. https://www.biorxiv.org/content/10.1101/2023.02.15.528759v1
- Purvaja Marella, B.S. - Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)
Publications:
- Marella P, Yahn GB, Kang J, Jadavji NM. (2022) The impact of homocysteine on ischemic stroke and dementia: an updated review of clinical studies and mechanisms in Advances in Health and Disease. Nova Science Publishers Inc.
- Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.
- PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring. https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1
- Gyllian Yahn, MBS - Master of Biomedical Science and Doctor of Dental Medicine Student
Publications:
- Yahn GB, Abato JE, Jadavji NM (2021) Role of vitamin B12 deficiency in ischemic stroke risk and outcome. Neural Regen Res 16(3):470-474.
- Yahn GB, Leoncio J, Jadavji NM (2021) The role of dietary supplementation of one-carbon metabolism on stroke outcome. Current Opinion in Clinical Nutrition and Metabolic Care: doi: 10.1097/MCO.0000000000000743 (invited)
- Yahn GB, Wasek B, Bottiglieri T, Malysheva O, Caudill MA, Jadavji NM. (2021) A dietary vitamin B12 deficiency impairs motor function and changes neuronal survival and choline metabolism after ischemic stroke to the sensorimotor cortex in middle aged male and female mice. https://www.biorxiv.org/content/10.1101/2021.08.17.456684v3
- Marella P, Yahn GB, Kang J, Jadavji NM. (2022) The impact of homocysteine on ischemic stroke and dementia: an updated review of clinical studies and mechanisms in Advances in Health and Disease. Nova Science Publishers Inc.
- Yahn GB, Wasek B, Bottiglieri T, Malysheva O, Caudill MA, Jadavji NM (2023) A dietary vitamin B12 deficiency impairs motor function and changes neuronal survival and choline metabolism after ischemic stroke to the sensorimotor cortex in middle aged male and female mice. Nutritional Neuroscience, In Press https://doi.org/10.1080/1028415X.2023.2188639.
- Sapna Viridi, MBS - Doctor of Osteopathic Medicine Student
Publication:
- Virdi S, Jadavji NM* The impact of maternal folates on brain development and function after birth. Metabolites 12(9): 876
- Jesse Jauhal, B.S. - Master of Biomedical Sciences Student
Publication:
- Clementson M, Jauhal J, Jadavji NM* (2023) Dietary B-vitamins deficiencies and maternal over supplementation on neurodevelopment: an updated narrative. Vitamins and Minerals in Neurological Disorders. Editor: Colin Martin, Vinood Patel, and Victor Preedy. Elsevier. p661-672. (invited).
- Clementson M, Jauhal J, Jadavji NM* Dietary B-vitamins deficiencies and maternal over supplementation on neurodevelopment: an updated narrative. Vitamins and Minerals in Neurological Disorders. Editor: Colin Martin, Vinood Patel, and Victor Preedy. Elsevier. (invited).
- PREPRINT Hurley L, Jauhal J, Ille S, Pull K, Malysheva OV, Jadavji NM. (2023) Maternal dietary deficiencies in one-carbon metabolism during early neurodevelopment result in larger damage volume, reduced neurodegeneration and neuroinflammation and changes in choline metabolites after ischemic stroke in middle-aged offspring. https://www.biorxiv.org/content/10.1101/2023.02.15.528759v1
- Jeemin Kang, MA - Doctor of Osteopathic Medicine Student
Publication:
- Marella P, Yahn GB, Kang J, Jadavji NM. The impact of homocysteine on ischemic stroke and dementia: an updated review of clinical studies and mechanisms in Advances in Health and Disease. Nova Science Publishers Inc.
- Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM. Maternal dietary choline deficiencies during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. https://www.biorxiv.org/content/10.1101/2022.08.23.505040v1
- Sarah Coonrod, BSc. - College Veterinary Medicine Fellow, Summer 2021
Publication
- Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.
- PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring. https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1
- Agnes S. Pascual, M.S. – Senior Research Specialist
- Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. (2022) Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. Nutrients, 14(14), 2960; https://doi.org/10.3390/nu14142960
- PREPRINT: Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. https://www.biorxiv.org/content/10.1101/2022.04.04.487028v2
- Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.
- PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring. https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1
- McCoy Clementson, B.S. - Doctor of Osteopathic Medicine Student
(Kenneth Saurez Research Fellow)
Publications:
- Clementson M, Jauhal J, Jadavji NM* (2023) Dietary B-vitamins deficiencies and maternal over supplementation on neurodevelopment: an updated narrative. Vitamins and Minerals in Neurological Disorders. Editor: Colin Martin, Vinood Patel, and Victor Preedy. Elsevier. (invited).
- Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.
- PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring. https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1
- Joshua Poole, B.S. - Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)
Publications:
- Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. (2022) Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. Nutrients, 14(14), 2960; https://doi.org/10.3390/nu14142960
- PREPRINT: Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. https://www.biorxiv.org/content/10.1101/2022.04.04.487028v2
- Shaley Jackson, B.Sc. - Research Assistant
Publication:
- Pull K, Folk R, Kang J, Jackson S, Gusek B, Esfandiarei M, Jadavji NM. Maternal dietary choline deficiencies during pregnancy and lactation reduce cerebral blood flow in 3-month-old female mice offspring following ischemic stroke to the sensorimotor cortex. https://www.biorxiv.org/content/10.1101/2022.08.23.505040v1
- Sean North, B.Sc. - Research Assistant
Publication
- Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. (2022) Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. Nutrients, 14(14), 2960; https://doi.org/10.3390/nu14142960
- PREPRINT: Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. https://www.biorxiv.org/content/10.1101/2022.04.04.487028v2
- Neha Kwatra, B.Sc. - Research Assistant
Publications:
- Kwarta N, Jadavji NM. (2020) How changes in our genes impact outcome after stroke. Atlas of Science. https://atlasofscience.org/how-changes-in-our-genes-impact-outcome-after-stroke/
- Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM (2020) The antioxidant role of one-carbon metabolism on stroke. Antioxidants. 9(11):1141 (invited)
- Bennett C, Green J, Ciancio M, Goral J, Pitstick L, Pytynia M, Meyer A, Kwatra N, Jadavji NM*. (2021) Dietary folic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice. Nutritional Neuroscience: In Press
- Poole J, Jasbi J, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. https://www.biorxiv.org/content/10.1101/2022.04.04.487028v2
- Poole J, Jasbi J, Pascual AS, North S, Kwarta N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. (2022) Ischemic stroke and dietary vitamin B12 deficiency in old-aged females impaired motor function, increased ischemic damage size, and changed metabolite profiles in brain and cecum tissue. Nutrients, 14(14), 2960; https://doi.org/10.3390/nu14142960
- Jeannine Leoncio, B.S. - Research Assistant
Publication:
1. Yahn GB, Leoncio J, Jadavji NM The role of dietary supplementation of one-carbon metabolism on stroke
outcome. Current Opinion in Clinical Nutrition and Metabolic Care: doi: 10.1097/MCO.0000000000000743 (invited)
- Calli Bennett, B.Sc. - Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)
Publications
- Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM (2020) The antioxidant role of one-carbon metabolism on stroke. Antioxidants. 9(11):1141 (invited)
- Bennett C, Green J, Ciancio M, Goral J, Pitstick L, Pytynia M, Meyer A, Kwatra N, Jadavji NM*. (2021) Dietaryfolic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice. Nutritional Neuroscience: In Press
- Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM. (2023) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring, Neural Regeneration Research. 18:2443-2448.
- PREPRINT: Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill M, Jadavji NM (2022) Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring. https://www.biorxiv.org/content/10.1101/2022.09.28.509960v1
- Kassidy Burgess, BS - College of Veterinary Medicine Fellow
Publication
1. Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM. (2020) The antioxidant role of one- carbon
metabolism on stroke. Antioxidants. 9(11):1141 (invited)
- Forrest Bethel, MSc - Doctor of Osteopathic Medicine Student (Kenneth Saurez Research Fellow)
Publication
1. Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM. (2020) The antioxidant role of one-carbon
metabolism on stroke. Antioxidants. 9(11):1141 (invited)
- Chelsea Adamson, MPH – Research Assistant
Publication
1. Al Rubaye H, Adamson C, Jadavji NM (2020) The role of maternal diet on offspring gut microbiota
development. Journal of Neuroscience Research. PMID: 32112450
- Jamie Abato, BSc - Research Assistant
Publications:
- Abato JE, Moftah M, Cron GO, Smith PD, Jadavji NM*. (2020) Methylenetetrahydrofolate reductase deficiency alters cellular response after ischemic stroke in male mice. Nutritional Neuroscience. http://dx.doi.org/10.1080/1028415X.2020.1769412.
- Yahn GB, Abato JE, Jadavji NM (2021) Role of vitamin B12 deficiency in ischemic stroke risk and outcome. Neural Regen Res 16(3):470-474.