Selected Peer-Reviewed Publications
Link to Publications on PubMed
Graduate and undergraduate trainees are italicized, *denotes corresponding author, +denotes shared first authorship
Rando HM, Wellhausen N Ghosh, Dattoli AA, Hu F, Lee AJ, Rafizadeh DN, Byrd JB, Qi Y, S Y, Field JM, Guebila MB, Jadavji NM, Lordan R, Shelly AN, Brueffer C, Wang J, Goel RR, Park YS COVID-19 Review Consortium, Boca SM, Gitter A, Greene CS. Identification and Development of Therapeutics for COVID-19. mSystems. 6(6): e000233-32
Lordan R, Rando HM, COVID-19 Review Consortium (Jadavji NM) Greene CS. Dietary Supplements and Nutraceuticals under Investigation for COVID-19 Prevention and Treatment. mSystems. 6(3): e00122-21
Auer S, Haelterman NA, Weissgerber TL, Erlich JC, Susilaradeya D, Julkowska M, Gazda MA, Reproducibility for Everyone Team, Schwessinger B*, Jadavji NM* (2021) Reproducibility for everyone: a community-led initiative with global reach in reproducible research training. eLife: https://elifesciences.org/articles/64719?fbclid=IwAR0VM94vkMqJldb26rJvjGmj7DQ-ifr0gds1cC1YNu-Pq74F42HUeCON6_I#content
Bennett C, Green J, Ciancio M, Goral J, Pitstick L, Pytynia M, Meyer A, Kwatra N, Jadavji NM*. (2021) Dietary folic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice. Nutritional Neuroscience: In Press. DOI: 10.1080/1028415X.2021.1932242. PMID: 34042561.
Sarabipour S, Hainer SJ, Arslan FN, Winde CM, Furlong E, Bielczyk N, Jadavji NM, Shah AP, Davla S, Asby N. (2021) Building and sustaining mentor interactions as a mentee. The FEBS Journal. DOI: 10.1111/febs.15823
Yahn GB, Leoncio J, Jadavji NM* (2021) The role of dietary supplementation of one-carbon metabolism on stroke outcome. Current Opinion in Clinical Nutrition and Metabolic Care: doi: 10.1097/MCO.0000000000000743 (invited)
Sarabipour S+, Hainer SJ+, Furlong E+, Jadavji NM+, de Winde CM, Bielczyk N, Shah AP. (2021)Ten simple rules for writing effective and supportive recommendation letters. The FEBS Journal: In Press
de Winde CM, Sarabipour S, Carignano H, Davla D, Eccles D, Hainer SJ, Haidar M, Iiangovan V, Jadavji NM, Kritsiligkou, Lee TY Olafsdottir, Symmons O. (2021) Towards inclusive funding practices for early career researchers. Journal of Science Policy and Governance (In Press)
Yahn GB, Abato JE, Jadavji NM* (2021) Role of vitamin B12 deficiency in ischemic stroke risk and outcome. Neural Regen Res 16(3):470-474.
Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM*. (2020) The antioxidant role of one-carbon metabolism on stroke. Antioxidants. 9(11):1141(invited)
Fernandes JD, Sarabipor A, Smith CT, Niemi NM, Jadavji NM, Kozik AJ, Holehouse AS, Pejaver V, Symmons O, Filho AWB, Haage A. (2020) Insights from a survey-based analysis of the academic job market. eLife. 9: e54097 DOI: 10.7554/eLife.54097
Abato JE, Moftah M, Cron GO, Smith PD, Jadavji NM* (2020) Methylenetetrahydrofolate reductase deficiency alters cellular response after ischemic stroke in male mice. Nutritional Neuroscience. http://dx.doi.org/10.1080/1028415X.2020.1769412
Van Benthem K, Corker C, Inoue J, Adi MN, Jadavji NM* (2020) The changing postdoc and key predictors of satisfaction with professional training. Studies in Graduate and Postdoctoral Research. 11:123-142.
Al Rubaye H, Adamson C, Jadavji NM* (2020) The role of maternal diet on offspring gut microbiota development. Journal of Neuroscience Research. https://onlinelibrary.wiley.com/doi/abs/10.1002/jnr.24605 PMID: 32112450
Jadavji NM*, Mosnier H, Kelly E, Lawrence K, Cruickshank S, Stacey S, McCall A, Dhatt S, Arning E, Bottiglieri T, Smith PD (2019) One-carbon metabolism supplementation improves outcome after stroke in aged male MTHFR-deficient mice. Neurobiology of disease. 132, 104613. PMID: 31525435.
Murray LK, Jadavji NM* (In Press). The role of B-vitamin metabolism in Parkinson’s disease onset, pathology, and mechanisms. Nutrition Research Reviews. 32 (2), 218-230. PMID: 31303188
Moftah M, Jadavji NM* The role of behavioral training in reducing functional impairments after stroke. Neural Regeneration Research. 14:1507-08. PMID: 31089041. (invited).
Jadavji NM*, Murray LK, Emmerson JT, Rudyk CA, Hayley S, Smith PD. (2019) A genetic deficiency in one-carbon metabolism increases oxidative stress in a mouse mode of Parkinson’s disease. Toxicological Sciences.169 (1), 25-33. PMID: 30726997
Prieur E, Jadavji NM* (2019). Assessing spatial working memory using the spontaneous y-maze alternation test in mice. Bio Protocols, 9(3). Link to paper.
Jadavji NM*, Emmerson JT, Shanmugalingam U, Willmore WG, MacFarlane AJ, Smith P. (2018) MTHFR-deficiency increases vulnerability to stroke: in vitro and in vivo. Experimental Neurology, 309:14-22. PMID: 30055159
Murray LK, Smith MJ, Jadavji NM. (2018) Maternal over supplementation with folic acid and its impact on neurodevelopment of offspring. Nutrition Reviews. 76:708-721. PMID: 30010929
Zhang M+, Jadavji NM+*, Yoo HS, Smith PD. (2018) Human GDF-11 counteracts age-related short-term memory impairments in middle-aged mice. Behavioural Brain Research, 341:45-49. PMID: 29253511
Jadavji NM*. (2017) The integrated stress response is not a target for diffuse white matter injury in premature infants. Journal of Neuroscience, 37: 11772-1173. PMID: 29212946
Prieur EAK, Pjetri E, Ziesel S, Jadavji NM*. (2017) BHMT-deficiency results in brain atrophy and impairs memory in mice. Applied Physiology, Nutrition, and Metabolism, 42:1228-1231. PMID: 28715642
Emmerson JT, Murray LK, Jadavji NM*. (2017) Impact of one-carbon metabolism on neural regeneration in the central nervous system. Neural Regeneration,12: 1-2. PMID: 28852387 (invited).
Jadavji NM*, Emmerson JE, Willmore WG, MacFarlane AJ, Smith PD. (2017) B-vitamin and choline supplementation increases neuroplasticity and recovery after stroke. Neurobiology of disease, 103:89-100. PMID: 28396257
Bahous R, Jadavji NM, Deng L, Cosin-Tomas M, Lu J, Malysheva O, Leung KY, Ho MK, Pallas M, Kaliman P, Greene NDE, Bedell BJ, Caudill MA, Rozen R. (2017) High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring. Human Molecular Genetics, 26:888-900. PMID: 28069796
Dam K, Füchtemeier M, Farr TD, Boehm-Strum P, Foddis M, Dirnagl U, Jadavji NM*. (2017) Deficiencies in methylenetetrahydrofolate reductase and dietary folic acid alter choline metabolism during chronic hypoperfusion. Behavioral Brain Research, 321:201-208. PMID: 28087280
Emmerson JT, Jadavji NM*. (2016) Impact of maternal folic acid deficiencies on early childhood neurological development. Journal of Paediatric Reviews, 4: e6174 (invited).
Jadavji NM, Malysheva O, Caudill MA, Rozen R. (2015) MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in hippocampus in wild-type offspring. Neuroscience, 300: 1-9. PMID: 25956258
Jadavji NM*, Wieske F, Dirgnal U, Winter C. (2015) Methylenetetrahydrfolate reductase deficiency alters levels of monoamine neurotransmitters, glutamate and gamma aminobutyric acid in brain tissue. Molecular Genetics and Metabolism and Genetics Reports, 3:1-4. PMID: 26937386
Jadavji NM*, Farr TD, Lips L, Khalil A, Boehm-Sturm P, Harms C, Foddis M, Füchtemeier M, Dirnagl. (2015) Elevated levels of homocysteine, deficiencies in folic acid and uracil-DNA glycosylase impair learning in a mouse model of vascular cognitive impairment. Behavioural Brain Research, 283: 215-226. PMID: 2565513
Jadavji NM, Bahous R, Deng L, Wang XL, Malysheva O, Caudill MA, Bedell BJ, Rozen R. (2014) A mouse model for genetic variation in methionine synthase reductase exhibits mild hyperhomocysteinemia, short-term memory impairment and biochemical changes in hippocampus. Biochemical Journal, 461:205-12. PMID: 24800750
Jadavji NM, Deng L, Leclerc D, Malysheva O, Caudill MA, Bedell BJ, Rozen R. (2012) Methylenetetrahydrofolate reductase deficiency in mice impairs motor and cognitive function, with morphological and neurobiochemical changes in cerebellum and hippocampus. Molecular Genetics and Metabolism, 106:149-159. PMID: 22521626
Jadavji NM, Metz GA. (2009) Both pre- and post-treatment with experiential therapy is beneficial in 6-OHDA dopamine-depleted rat. Neuroscience, 158:373-86. PMID: 19032978
Smith LK, Jadavji NM, Colwell KL, Perehudoff SK Metz GA. (2008) Stress and glucocorticoids accelerate dopaminergic apoptosis and exaggerate motor symptoms in a rat model of Parkinson’s disease. European Journal of Neuroscience, 27: 2133-2146. PMID: 18412632
Jadavji NM, Kolb B and Metz GA. (2006) Enriched environment improves motor function in intact and dopamine-depleted rats: implications for Parkinson’s disease. Neuroscience, 140: 1127-1138. PMID: 1667892
Link to Publications on PubMed
Graduate and undergraduate trainees are italicized, *denotes corresponding author, +denotes shared first authorship
Rando HM, Wellhausen N Ghosh, Dattoli AA, Hu F, Lee AJ, Rafizadeh DN, Byrd JB, Qi Y, S Y, Field JM, Guebila MB, Jadavji NM, Lordan R, Shelly AN, Brueffer C, Wang J, Goel RR, Park YS COVID-19 Review Consortium, Boca SM, Gitter A, Greene CS. Identification and Development of Therapeutics for COVID-19. mSystems. 6(6): e000233-32
Lordan R, Rando HM, COVID-19 Review Consortium (Jadavji NM) Greene CS. Dietary Supplements and Nutraceuticals under Investigation for COVID-19 Prevention and Treatment. mSystems. 6(3): e00122-21
Auer S, Haelterman NA, Weissgerber TL, Erlich JC, Susilaradeya D, Julkowska M, Gazda MA, Reproducibility for Everyone Team, Schwessinger B*, Jadavji NM* (2021) Reproducibility for everyone: a community-led initiative with global reach in reproducible research training. eLife: https://elifesciences.org/articles/64719?fbclid=IwAR0VM94vkMqJldb26rJvjGmj7DQ-ifr0gds1cC1YNu-Pq74F42HUeCON6_I#content
Bennett C, Green J, Ciancio M, Goral J, Pitstick L, Pytynia M, Meyer A, Kwatra N, Jadavji NM*. (2021) Dietary folic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice. Nutritional Neuroscience: In Press. DOI: 10.1080/1028415X.2021.1932242. PMID: 34042561.
Sarabipour S, Hainer SJ, Arslan FN, Winde CM, Furlong E, Bielczyk N, Jadavji NM, Shah AP, Davla S, Asby N. (2021) Building and sustaining mentor interactions as a mentee. The FEBS Journal. DOI: 10.1111/febs.15823
Yahn GB, Leoncio J, Jadavji NM* (2021) The role of dietary supplementation of one-carbon metabolism on stroke outcome. Current Opinion in Clinical Nutrition and Metabolic Care: doi: 10.1097/MCO.0000000000000743 (invited)
Sarabipour S+, Hainer SJ+, Furlong E+, Jadavji NM+, de Winde CM, Bielczyk N, Shah AP. (2021)Ten simple rules for writing effective and supportive recommendation letters. The FEBS Journal: In Press
de Winde CM, Sarabipour S, Carignano H, Davla D, Eccles D, Hainer SJ, Haidar M, Iiangovan V, Jadavji NM, Kritsiligkou, Lee TY Olafsdottir, Symmons O. (2021) Towards inclusive funding practices for early career researchers. Journal of Science Policy and Governance (In Press)
Yahn GB, Abato JE, Jadavji NM* (2021) Role of vitamin B12 deficiency in ischemic stroke risk and outcome. Neural Regen Res 16(3):470-474.
Burgess K, Bennett C, Mosnier H, Kwatra N, Bethel B, Jadavji NM*. (2020) The antioxidant role of one-carbon metabolism on stroke. Antioxidants. 9(11):1141(invited)
Fernandes JD, Sarabipor A, Smith CT, Niemi NM, Jadavji NM, Kozik AJ, Holehouse AS, Pejaver V, Symmons O, Filho AWB, Haage A. (2020) Insights from a survey-based analysis of the academic job market. eLife. 9: e54097 DOI: 10.7554/eLife.54097
Abato JE, Moftah M, Cron GO, Smith PD, Jadavji NM* (2020) Methylenetetrahydrofolate reductase deficiency alters cellular response after ischemic stroke in male mice. Nutritional Neuroscience. http://dx.doi.org/10.1080/1028415X.2020.1769412
Van Benthem K, Corker C, Inoue J, Adi MN, Jadavji NM* (2020) The changing postdoc and key predictors of satisfaction with professional training. Studies in Graduate and Postdoctoral Research. 11:123-142.
Al Rubaye H, Adamson C, Jadavji NM* (2020) The role of maternal diet on offspring gut microbiota development. Journal of Neuroscience Research. https://onlinelibrary.wiley.com/doi/abs/10.1002/jnr.24605 PMID: 32112450
Jadavji NM*, Mosnier H, Kelly E, Lawrence K, Cruickshank S, Stacey S, McCall A, Dhatt S, Arning E, Bottiglieri T, Smith PD (2019) One-carbon metabolism supplementation improves outcome after stroke in aged male MTHFR-deficient mice. Neurobiology of disease. 132, 104613. PMID: 31525435.
Murray LK, Jadavji NM* (In Press). The role of B-vitamin metabolism in Parkinson’s disease onset, pathology, and mechanisms. Nutrition Research Reviews. 32 (2), 218-230. PMID: 31303188
Moftah M, Jadavji NM* The role of behavioral training in reducing functional impairments after stroke. Neural Regeneration Research. 14:1507-08. PMID: 31089041. (invited).
Jadavji NM*, Murray LK, Emmerson JT, Rudyk CA, Hayley S, Smith PD. (2019) A genetic deficiency in one-carbon metabolism increases oxidative stress in a mouse mode of Parkinson’s disease. Toxicological Sciences.169 (1), 25-33. PMID: 30726997
Prieur E, Jadavji NM* (2019). Assessing spatial working memory using the spontaneous y-maze alternation test in mice. Bio Protocols, 9(3). Link to paper.
Jadavji NM*, Emmerson JT, Shanmugalingam U, Willmore WG, MacFarlane AJ, Smith P. (2018) MTHFR-deficiency increases vulnerability to stroke: in vitro and in vivo. Experimental Neurology, 309:14-22. PMID: 30055159
Murray LK, Smith MJ, Jadavji NM. (2018) Maternal over supplementation with folic acid and its impact on neurodevelopment of offspring. Nutrition Reviews. 76:708-721. PMID: 30010929
Zhang M+, Jadavji NM+*, Yoo HS, Smith PD. (2018) Human GDF-11 counteracts age-related short-term memory impairments in middle-aged mice. Behavioural Brain Research, 341:45-49. PMID: 29253511
Jadavji NM*. (2017) The integrated stress response is not a target for diffuse white matter injury in premature infants. Journal of Neuroscience, 37: 11772-1173. PMID: 29212946
Prieur EAK, Pjetri E, Ziesel S, Jadavji NM*. (2017) BHMT-deficiency results in brain atrophy and impairs memory in mice. Applied Physiology, Nutrition, and Metabolism, 42:1228-1231. PMID: 28715642
Emmerson JT, Murray LK, Jadavji NM*. (2017) Impact of one-carbon metabolism on neural regeneration in the central nervous system. Neural Regeneration,12: 1-2. PMID: 28852387 (invited).
Jadavji NM*, Emmerson JE, Willmore WG, MacFarlane AJ, Smith PD. (2017) B-vitamin and choline supplementation increases neuroplasticity and recovery after stroke. Neurobiology of disease, 103:89-100. PMID: 28396257
Bahous R, Jadavji NM, Deng L, Cosin-Tomas M, Lu J, Malysheva O, Leung KY, Ho MK, Pallas M, Kaliman P, Greene NDE, Bedell BJ, Caudill MA, Rozen R. (2017) High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring. Human Molecular Genetics, 26:888-900. PMID: 28069796
Dam K, Füchtemeier M, Farr TD, Boehm-Strum P, Foddis M, Dirnagl U, Jadavji NM*. (2017) Deficiencies in methylenetetrahydrofolate reductase and dietary folic acid alter choline metabolism during chronic hypoperfusion. Behavioral Brain Research, 321:201-208. PMID: 28087280
Emmerson JT, Jadavji NM*. (2016) Impact of maternal folic acid deficiencies on early childhood neurological development. Journal of Paediatric Reviews, 4: e6174 (invited).
Jadavji NM, Malysheva O, Caudill MA, Rozen R. (2015) MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in hippocampus in wild-type offspring. Neuroscience, 300: 1-9. PMID: 25956258
Jadavji NM*, Wieske F, Dirgnal U, Winter C. (2015) Methylenetetrahydrfolate reductase deficiency alters levels of monoamine neurotransmitters, glutamate and gamma aminobutyric acid in brain tissue. Molecular Genetics and Metabolism and Genetics Reports, 3:1-4. PMID: 26937386
Jadavji NM*, Farr TD, Lips L, Khalil A, Boehm-Sturm P, Harms C, Foddis M, Füchtemeier M, Dirnagl. (2015) Elevated levels of homocysteine, deficiencies in folic acid and uracil-DNA glycosylase impair learning in a mouse model of vascular cognitive impairment. Behavioural Brain Research, 283: 215-226. PMID: 2565513
Jadavji NM, Bahous R, Deng L, Wang XL, Malysheva O, Caudill MA, Bedell BJ, Rozen R. (2014) A mouse model for genetic variation in methionine synthase reductase exhibits mild hyperhomocysteinemia, short-term memory impairment and biochemical changes in hippocampus. Biochemical Journal, 461:205-12. PMID: 24800750
Jadavji NM, Deng L, Leclerc D, Malysheva O, Caudill MA, Bedell BJ, Rozen R. (2012) Methylenetetrahydrofolate reductase deficiency in mice impairs motor and cognitive function, with morphological and neurobiochemical changes in cerebellum and hippocampus. Molecular Genetics and Metabolism, 106:149-159. PMID: 22521626
Jadavji NM, Metz GA. (2009) Both pre- and post-treatment with experiential therapy is beneficial in 6-OHDA dopamine-depleted rat. Neuroscience, 158:373-86. PMID: 19032978
Smith LK, Jadavji NM, Colwell KL, Perehudoff SK Metz GA. (2008) Stress and glucocorticoids accelerate dopaminergic apoptosis and exaggerate motor symptoms in a rat model of Parkinson’s disease. European Journal of Neuroscience, 27: 2133-2146. PMID: 18412632
Jadavji NM, Kolb B and Metz GA. (2006) Enriched environment improves motor function in intact and dopamine-depleted rats: implications for Parkinson’s disease. Neuroscience, 140: 1127-1138. PMID: 1667892